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Neuropeptide Research
Peptides studied for their proposed effects on neuroplasticity, BDNF expression, and neuroprotective mechanisms in preclinical models.
Semax: Neuroplasticity and BDNF
Semax is a synthetic analogue of ACTH(4-7) studied in Russian research for neurological mechanisms. Its primary mechanism of interest is the upregulation of BDNF (brain-derived neurotrophic factor) — a protein studied in neuroplasticity and neuroprotection models. Published research has documented Semax-associated increases in BDNF and NGF expression in hippocampal tissue in rodent models, making it one of the most studied neuropeptides in the Russian research literature.
Selank: GABAergic and Serotonergic Research
Selank is a heptapeptide that has been observed to modulate the expression of genes related to the serotonergic, dopaminergic, and GABAergic systems in research models. Preclinical studies have examined its effects on GABAergic signalling, and Russian clinical research has explored its effects on anxiety-related pathways. All content here is for research and educational purposes only.
Dihexa: Synaptic Formation
Dihexa is an oligopeptide derived from angiotensin IV that has been studied for its activity in synaptogenesis — the formation of new synaptic connections — in animal models. Preclinical research has indicated activity in synaptic formation models several orders of magnitude more active than BDNF. It is among the compounds of interest in neuropeptide research literature. For in vitro research use only.
Delivery Routes in Neuropeptide Research
Many neuropeptides in the research literature are studied via intranasal routes — Semax and Selank have been examined using nasal spray delivery in published research, which is proposed to provide more direct access to the olfactory bulb. Delivery route is an important variable to consider when reviewing published research on peptides studied for CNS-related mechanisms.
Research Disclaimer: All content on this page is provided for educational and informational purposes only and relates strictly to published preclinical research. Silver Peptide products are supplied for in vitro laboratory research use only. They are not approved by the MHRA, FDA, or any regulatory body for human consumption, injection, or veterinary use. They are not medicines and must not be used as such. Nothing on this page constitutes medical advice.